A Typeface Is a Tone of Voice
Readers hear a page before they read it. The typeface decides which voice is doing the talking.
Ivo Lindqvist, Contributing writer

Before a single word is read, the reader has already formed an opinion. They have decided whether this is serious or casual, careful or hurried, expensive or free. They did it from the shapes of the letters, and they did it without noticing.
That is not decoration. That is the first sentence of the page, delivered before your first sentence gets a turn.
What the shapes actually say
A high-contrast serif with sharp terminals reads as considered and slightly formal, which is why it suits long argument and looks absurd on a warning message. A geometric sans reads as neutral and modern, which is why it suits interfaces and drains the warmth out of a personal essay. A humanist sans sits between the two and is the safest default in the language.
None of these is better. They are different registers, and the only real mistake is picking one register and writing in another.
Setting an anxious message in a cheerful typeface does not make the message cheerful. It makes the product sound as though it is not listening.
Two faces are enough
Most sites need one face for reading and one for structure, and the pairing works when the two are clearly different rather than nearly the same. Two sans-serifs of similar weight and width do not read as a pair, they read as a mistake, and every visitor gets a faint sense that something is off without being able to say what.
If you want a single-family site, use one family and get your contrast from weight and size instead. That is a real choice and often the more disciplined one.
The parts that matter more than the family
A well-set common typeface beats a badly-set beautiful one every time. In order of impact:
- Line length. Somewhere between 60 and 80 characters for body text. Nothing rescues a line that runs the full width of a desktop screen.
- Line height. Roughly 1.5 for body copy, tighter as the type gets larger, because long lines need more vertical room to track back to.
- Size. Sixteen pixels is a floor for body text, not a target. Editorial reading is comfortable a good deal above it.
- Weight contrast. Headings earn their prominence through size and weight together, not either one pushed to an extreme.
Read it out loud
The final check is not visual. Read a paragraph of the real copy, set in the real face, at the real size, out loud. If the voice you hear in your head does not match the voice the writing intends, the face is wrong, however good it looks in the specimen.
Type is not the surface on top of the writing. It is part of the writing, and it is already speaking.